Pierre Beauparlant Selected Research

1- (2- (2- (2- (2- methoxyethoxy)ethoxy)ethoxy)ethoxycarbonyloxymethyl)- 4- (N'- cyano- N''- (6- (4- chlorophenoxy)hexyl)- N- guanidino)pyridinium

11/2009	The small molecule GMX1778 is a potent inhibitor of NAD+ biosynthesis: strategy for enhanced therapy in nicotinic acid phosphoribosyltransferase 1-deficient tumors.
6/2009	Preclinical development of the nicotinamide phosphoribosyl transferase inhibitor prodrug GMX1777.

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Pierre Beauparlant Research Topics

Disease

4	Neoplasms (Cancer) 11/2009 - 03/2003
1	Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker) 08/2021
1	Glioblastoma (Glioblastoma Multiforme) 11/2009
1	Neuroblastoma 11/2009
1	Sarcoma (Soft Tissue Sarcoma) 11/2009
1	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 06/2009
1	Carcinoma (Carcinomatosis) 06/2009
1	Multiple Myeloma 06/2009
1	Lymphoma (Lymphomas) 06/2009

Drug/Important Bio-Agent (IBA)

2	N- (6- chlorophenoxyhexyl)- N''- cyano- N''- 4- pyridylguanidine (CHS 828)IBA 11/2009 - 06/2009
2	Proteins (Proteins, Gene)FDA Link 11/2009 - 12/2007
2	1- (2- (2- (2- (2- methoxyethoxy)ethoxy)ethoxy)ethoxycarbonyloxymethyl)- 4- (N'- cyano- N''- (6- (4- chlorophenoxy)hexyl)- N- guanidino)pyridiniumIBA 11/2009 - 06/2009
2	NAD (NADH)IBA 11/2009 - 06/2009
1	Transforming Growth Factor beta (TGF-beta)IBA 08/2021
1	nicotinate phosphoribosyltransferaseIBA 11/2009
1	ProdrugsIBA 11/2009
1	Messenger RNA (mRNA)IBA 11/2009
1	CaspasesIBA 03/2003
1	Cytotoxins (Cytolysins)IBA 03/2003

Therapy/Procedure

1	Therapeutics 11/2009
1	Intravenous Infusions 06/2009
1	Intravenous Injections 06/2009